CD8 T Cells fromMice Transnuclear for a TCR that Recognizes a Single H-2K-Restricted MHV68 Epitope Derived from gB-ORF8 Help Control Infection
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Citation Sehrawat, Sharvan, Oktay Kirak, Paul-Albert Koenig, Marisa K. Isaacson, Sofia Marques, Gunes Bozkurt, J. Pedro Simas, Rudolph Jaenisch, and Hidde L. Ploegh. “CD8+ T Cells from Mice Transnuclear for a TCR That Recognizes a Single H-2KbRestricted MHV68 Epitope Derived from gB-ORF8 Help Control Infection.” Cell Reports 1, no. 5 (May 2012): 461–471. As Published http://dx.doi.org/10.1016/j.celrep.2012.03.009 Publisher Elsevier
منابع مشابه
CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection.
To study the CD8(+) T cell response against a mouse γ-herpes virus, we generated K(b)-MHV-68-ORF8(604-612)RAG(-/-) CD8(+) T cell receptor transnuclear (TN) mice as a source of virus-specific CD8(+) T cells. K(b)-ORF8-Tet(+) CD8(+) T cells, expanded in the course of a resolving MHV-68 infection, served as a source of nucleus donors. Various in vivo and ex vivo assay criteria demonstrated the fin...
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تاریخ انتشار 2012